7U7M
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D (A, B, C, D) | ATP-sensitive inward rectifier potassium channel 11 | polymer | 390 | 43661.8 | 4 | UniProt (P70673) Pfam (PF01007) Pfam (PF17655) | Rattus norvegicus (Norway rat) | BIR,Inward rectifier K(+) channel Kir6.2,Potassium channel,inwardly rectifying subfamily J member 11 |
2 | E (E) | ATP-binding cassette sub-family C member 8 | polymer | 1582 | 177333.6 | 1 | UniProt (Q09427) Pfam (PF00664) Pfam (PF00005) | Cricetus cricetus (black-bellied hamster) | SUR1, Sulfonylurea receptor 1 |
3 | F (E) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 351980.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 507.2 | |
All* | Total formula weight | 352487.8 |