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7U7M

Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
ATP-sensitive inward rectifier potassium channel 11polymer39043661.84UniProt (P70673)
Pfam (PF01007)
Pfam (PF17655)
Rattus norvegicus (Norway rat)BIR,Inward rectifier K(+) channel Kir6.2,Potassium channel,inwardly rectifying subfamily J member 11
2E
(E)
ATP-binding cassette sub-family C member 8polymer1582177333.61UniProt (Q09427)
Pfam (PF00664)
Pfam (PF00005)
Cricetus cricetus (black-bellied hamster)SUR1, Sulfonylurea receptor 1
3F
(E)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight351980.6
Non-Polymers*Number of molecules1
Total formula weight507.2
All*Total formula weight352487.8
*Water molecules are not included.

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PDB entries from 2024-11-06

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