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7U79

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 140s

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')polymer123637.41synthetic construct
3C
(P)
DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3')polymer92755.81synthetic construct
4D, E, K
(A, P)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5F, G, H
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
6I
(A)
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (DGT)
7J
(A)
DIPHOSPHATEnon-polymer173.91Chemie (DPO)
8L, M, N
(A, T, P)
waterwater18.0527Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight55010.9
Non-Polymers*Number of molecules8
Total formula weight1030.3
All*Total formula weight56041.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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