7U6D

Head region of insulin receptor ectodomain (A-isoform) bound to the non-insulin agonist IM459

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	IM459	polymer	32	4000.6	1		synthetic construct
2	B, C (C, B)	Isoform Short of Insulin receptor	polymer	916	104607.7	2	UniProt (P06213) Pfam (PF01030) Pfam (PF00757) Pfam (PF00041) Pfam (PF17870)	Homo sapiens (human)	IR

Sequence modifications

C, B: 1 - 916 (UniProt: P06213)

PDB	External Database	Details
His 144	Tyr 171	conflict

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.