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7U4W

The ubiquitin-associated domain of human thirty-eight negative kinase-1 flexibly fused to the 1TEL crystallization chaperone via a 2-glycine linker and crystallized at traditional protein concentration

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATranscription factor ETV6,Non-receptor tyrosine-protein kinase TNK1polymer15517775.11UniProt (P41212)
UniProt (Q13470)
Pfam (PF02198)
In PDB
Homo sapiens (human)ETS translocation variant 6,ETS-related protein Tel1,Tel,CD38 negative kinase 1
2waterwater18.09Chemie (HOH)
Sequence modifications
A: 2 - 76 (UniProt: P41212)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 35Arg 80engineered mutation
Glu 67Val 112engineered mutation
Gly 77-linker
Gly 78-linker
A: 79 - 155 (UniProt: Q13470)
PDBExternal DatabaseDetails
Ala 99Cys 610engineered mutation
Ala 133Cys 644engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17775.1
All*Total formula weight17775.1
*Water molecules are not included.

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PDB entries from 2024-07-31

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