7U23

Single-chain LCDV-1 viral insulin-like peptide bound to IGF-1R ectodomain, leucine-zippered form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (E, F)	Insulin-like growth factor 1 receptor	polymer	952	108937.2	2	UniProt (P08069) Pfam (PF01030) Pfam (PF00757)	Homo sapiens (human)	Insulin-like growth factor I receptor,IGF-I receptor
2	C, D (C, D)	single-chain LCDV-1 viral insulin-like peptide	polymer	62	6726.7	2	Pfam (PF00049) UniProt (by SIFTS) (A0A9X9ZA31)	Lymphocystis disease virus 1

Sequence modifications

E, F: 1 - 905 (UniProt: P08069)

PDB	External Database	Details
Arg 906	-	expression tag
Met 907	-	expression tag
Lys 908	-	expression tag
Gln 909	-	expression tag
Leu 910	-	expression tag
Glu 911	-	expression tag
Asp 912	-	expression tag
Lys 913	-	expression tag
Val 914	-	expression tag
Glu 915	-	expression tag
Glu 916	-	expression tag
Leu 917	-	expression tag
Leu 918	-	expression tag
Ser 919	-	expression tag
Lys 920	-	expression tag
Asn 921	-	expression tag
Tyr 922	-	expression tag
His 923	-	expression tag
Leu 924	-	expression tag
Glu 925	-	expression tag
Asn 926	-	expression tag
Glu 927	-	expression tag
Val 928	-	expression tag
Ala 929	-	expression tag
Arg 930	-	expression tag
Leu 931	-	expression tag
Lys 932	-	expression tag
Lys 933	-	expression tag
Leu 934	-	expression tag
Val 935	-	expression tag
Gly 936	-	expression tag
Glu 937	-	expression tag
Arg 938	-	expression tag
Ser 939	-	expression tag
Ser 940	-	expression tag
Ser 941	-	expression tag
Glu 942	-	expression tag
Gln 943	-	expression tag
Lys 944	-	expression tag
Leu 945	-	expression tag
Ile 946	-	expression tag
Ser 947	-	expression tag
Glu 948	-	expression tag
Glu 949	-	expression tag
Asp 950	-	expression tag
Leu 951	-	expression tag
Asn 952	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	231327.9
All*	Total formula weight	231327.9

*Water molecules are not included.