7U0O

Crystal structure of an enoyl-[acyl-carrier-protein] reductase InhA from Mycobacterium fortuitum bound to NAD and NITD-916

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Enoyl-[acyl-carrier-protein] reductase [NADH]	polymer	277	29406.8	2	UniProt (A0A0N9XSE6) Pfam (PF13561)	Mycolicibacterium fortuitum
2	C, G (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	D, H (A, B)	6-[(4,4-dimethylcyclohexyl)methyl]-4-hydroxy-3-phenylpyridin-2(1H)-one	non-polymer		311.4	2	Chemie (3KY)
4	E, I (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5	F, J (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	K, L (A, B)	water	water		18.0	249	Chemie (HOH)

Sequence modifications

A, B: 1 - 269 (UniProt: A0A0N9XSE6)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58813.5
Non-Polymers*	Number of molecules	8
	Total formula weight	2066.6
All*	Total formula weight	60880.1

*Water molecules are not included.