7U0M

Crystal structure of a enoyl-[acyl-carrier-protein] reductase (InhA) from Mycobacterium abscessus bound to NAD and NITD-916

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Enoyl-[acyl-carrier-protein] reductase [NADH]	polymer	277	29695.1	2	UniProt (B1MC30) Pfam (PF13561) In PDB	Mycobacteroides abscessus
2	A, B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	A, B	6-[(4,4-dimethylcyclohexyl)methyl]-4-hydroxy-3-phenylpyridin-2(1H)-one	non-polymer		311.4	2	Chemie (3KY)
4	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5		water	water		18.0	667	Chemie (HOH)

Sequence modifications

A, B: 1 - 269 (UniProt: B1MC30)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59390.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1995.7
All*	Total formula weight	61385.8

*Water molecules are not included.