7U0M
Crystal structure of a enoyl-[acyl-carrier-protein] reductase (InhA) from Mycobacterium abscessus bound to NAD and NITD-916
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 277 | 29695.1 | 2 | UniProt (B1MC30) Pfam (PF13561) | Mycobacteroides abscessus | |
| 2 | C, F (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, G (A, B) | 6-[(4,4-dimethylcyclohexyl)methyl]-4-hydroxy-3-phenylpyridin-2(1H)-one | non-polymer | 311.4 | 2 | Chemie (3KY) | |||
| 4 | E, H (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 667 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 269 (UniProt: B1MC30)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59390.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1995.7 | |
| All* | Total formula weight | 61385.8 |
