7TZC
A drug and ATP binding site in type 1 ryanodine receptor
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | K, D, E, C | Calmodulin-1 | polymer | 150 | 16990.7 | 4 | UniProt (P0DP23) Pfam (PF13499) In PDB | Homo sapiens (human) | |
2 | F, H, J, O | Peptidyl-prolyl cis-trans isomerase FKBP1A | polymer | 107 | 11836.5 | 4 | UniProt (P62943) Pfam (PF00254) In PDB | Oryctolagus cuniculus (rabbit) | PPIase FKBP1A,12 kDa FK506-binding protein,12 kDa FKBP,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase |
3 | A, B, G, I | Ryanodine receptor 1 | polymer | 5037 | 565908.6 | 4 | UniProt (P11716) Pfam (PF08709) Pfam (PF01365) Pfam (PF02026) Pfam (PF08454) Pfam (PF06459) Pfam (PF00520) Pfam (PF02815) Pfam (PF00622) Pfam (PF21119) In PDB | Oryctolagus cuniculus (rabbit) | RYR-1,RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor |
4 | C, I, A, B, K... | CALCIUM ION | non-polymer | 40.1 | 20 | Chemie (CA) | |||
5 | I, A, B, G | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) | |||
6 | I, A, B, G | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
7 | I, A, B, G | CAFFEINE | non-polymer | 194.2 | 4 | Chemie (CFF) | |||
8 | I, A, B, G | 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid | non-polymer | 329.4 | 4 | Chemie (KVR) | |||
9 | I, A, B, G | (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 788.1 | 8 | Chemie (L9R) |
Sequence modifications
K, D, E, C: 0 - 148 (UniProt: P0DP23)
PDB | External Database | Details |
---|---|---|
His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 2378943.3 | |
Non-Polymers* | Number of molecules | 48 |
Total formula weight | 13520.1 | |
All* | Total formula weight | 2392463.4 |