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7TXW

Crystal structure of the complex of the malaria sexual stage protein and vaccine target Pfs25 with the Fab fragment of a transmission blocking antibody 1G2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
Fab fragment of monoclonal antibody 1G2 light chainpolymer21924226.91Mus musculus (mouse)
2B
(H)
Fab fragment of monoclonal antibody 1G2 heavy chainpolymer21923469.21Mus musculus (mouse)
3C
(A)
Ookinete surface protein P25polymer17118716.61UniProt (Q7KQL2)
Pfam (PF06247)
Plasmodium falciparum 3D7
4D
(L)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5E, F, G, K, L...
(L, H)
GLYCEROLnon-polymer92.16Chemie (GOL)
6H, I, N, O
(L, H)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
7J, P, Q, R, S...
(L, H)
ETHANOLnon-polymer46.16Chemie (EOH)
8U, V, W
(L, H, A)
waterwater18.0256Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight66412.8
Non-Polymers*Number of molecules17
Total formula weight1183.4
All*Total formula weight67596.1
*Water molecules are not included.

248942

PDB entries from 2026-02-11

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