7TUI
Structure of C. albicans FAS in an inhibited state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fatty acid synthase subunit alpha | polymer | 1885 | 207703.5 | 1 | UniProt (P43098) Pfam (PF18325) Pfam (PF18314) Pfam (PF00109) Pfam (PF02801) Pfam (PF01648) | Candida albicans (Yeast) | |
| 2 | B (B) | Fatty acid synthase subunit beta | polymer | 2037 | 228177.6 | 1 | UniProt (P34731) Pfam (PF13452) Pfam (PF22235) Pfam (PF01575) Pfam (PF00698) Pfam (PF17828) Pfam (PF16073) Pfam (PF08354) Pfam (PF17951) | Candida albicans (Yeast) | |
| 3 | C (B) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) |
Sequence modifications
A: 1 - 1885 (UniProt: P43098)
| PDB | External Database | Details |
|---|---|---|
| Val 350 | Ser 350 | conflict |
| Asp 351 | Arg 351 | conflict |
| Asn 353 | Lys 353 | conflict |
| Lys 354 | Gln 354 | conflict |
| Ala 357 | Leu 357 | conflict |
| Thr 814 | Pro 814 | conflict |
| Lys 1067 | Gln 1067 | conflict |
| Val 1124 | Ile 1124 | conflict |
| Glu 1445 | Lys 1445 | conflict |
| Ser 1743 | Asn 1743 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 435881.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 456.3 | |
| All* | Total formula weight | 436337.4 |
