7TUE

Crystal structure of Tapasin in complex with HLA-B*44:05 (T73C)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HLA class I histocompatibility antigen, B alpha chain	polymer	274	31804.2	1	Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (D5H3J5) In PDB	Homo sapiens
2	D	Tapasin	polymer	416	44739.6	1	UniProt (O15533) Pfam (PF07654) In PDB	Homo sapiens (human)	TPN,TPSN,NGS-17,TAP-associated protein,TAP-binding protein
3	B	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (human)

Sequence modifications

D: 1 - 381 (UniProt: O15533)

PDB	External Database	Details
Gly 382	-	expression tag
Gly 383	-	expression tag
Leu 384	-	expression tag
Glu 385	-	expression tag
Val 386	-	expression tag
Leu 387	-	expression tag
Phe 388	-	expression tag
Gln 389	-	expression tag
Gly 390	-	expression tag
Pro 391	-	expression tag
Gly 392	-	expression tag
Gly 393	-	expression tag
Gly 394	-	expression tag
Leu 395	-	expression tag
Asn 396	-	expression tag
Asp 397	-	expression tag
Ile 398	-	expression tag
Phe 399	-	expression tag
Glu 400	-	expression tag
Ala 401	-	expression tag
Gln 402	-	expression tag
Lys 403	-	expression tag
Ile 404	-	expression tag
Glu 405	-	expression tag
Trp 406	-	expression tag
His 407	-	expression tag
Glu 408	-	expression tag
Gly 409	-	expression tag
Gly 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	88423.2
All*	Total formula weight	88423.2

*Water molecules are not included.