7TQ1
Crystal structure of adaptive laboratory evolved sulfonamide-resistant Dihydropteroate Synthase (DHPS) from Escherichia coli in complex with 6-hydroxymethylpterin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dihydropteroate synthase | polymer | 285 | 30913.4 | 2 | UniProt (P0AC13) Pfam (PF00809) In PDB | Escherichia coli | DHPS,Dihydropteroate pyrophosphorylase |
| 2 | A, B | 6-HYDROXYMETHYLPTERIN | non-polymer | 193.2 | 2 | Chemie (HHR) | |||
| 3 | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 284 (UniProt: P0AC13)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Gly 187 | - | insertion |
| Phe 188 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61826.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 386.3 | |
| All* | Total formula weight | 62213.1 |
