7TPD

Integrin alpha IIB beta3 complex with EF5154

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Integrin alpha-IIb heavy chain	polymer	457	49516.0	2	UniProt (P08514) Pfam (PF01839)	Homo sapiens (human)
2	B, D (B, D)	Integrin beta-3	polymer	471	51958.8	2	UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372)	Homo sapiens (human)	Platelet membrane glycoprotein IIIa,GPIIIa
3	E, G (E, H)	Fab heavy chain	polymer	216	23339.1	2		Mus musculus (mouse)
4	F, H (F, L)	Fab light chain	polymer	214	23332.7	2		Mus musculus (mouse)
5	I (G)	beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G89225LT)
6	J, L (I, K)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
7	K (J)	beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G31886NL)
8	AA, BA, FA, GA, M... (C, D, A, B)	CALCIUM ION	non-polymer		40.1	12	Chemie (CA)
9	CA, DA, Q, R, S (C, A)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
10	EA, T (D, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
11	HA, W (D, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
12	IA, X (D, B)	(4-{[2-oxo-4-(piperidin-4-yl)piperazin-1-yl]acetyl}phenoxy)acetic acid	non-polymer		375.4	2	Chemie (IR7)
13	JA, KA, LA, MA, NA... (A, B, C, D, E...)	water	water		18.0	1010	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	296293.0
Branched	Number of molecules	4
	Total formula weight	2508.3
Non-Polymers*	Number of molecules	23
	Total formula weight	2203.1
All*	Total formula weight	301004.4

*Water molecules are not included.