7TL8

1.95A resolution structure of independent phosphoglycerate mutase from S. aureus in complex with a macrocyclic peptide inhibitor (Sa-D3)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	polymer	511	57316.7	1	UniProt (W8U5L7) Pfam (PF01676) Pfam (PF06415) UniProt (by SIFTS) (Q5HHP2)	Staphylococcus aureus	BPG-independent PGAM,Phosphoglyceromutase,iPGM
2	B (B)	Peptide Sa-D3	polymer	15	1810.0	1	BIRD (PRD_002492)	synthetic construct
3	C, D (A)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
4	E, F (A, B)	water	water		18.0	231	Chemie (HOH)

Sequence modifications

A: 1 - 505 (UniProt: W8U5L7)

PDB	External Database	Details
His 506	-	expression tag
His 507	-	expression tag
His 508	-	expression tag
His 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59126.7
Non-Polymers*	Number of molecules	2
	Total formula weight	109.9
All*	Total formula weight	59236.6

*Water molecules are not included.