7TI2
Structure of KPC-2 bound to RPX-7063 at 1.75A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbapenem-hydrolyzing beta-lactamase KPC | polymer | 277 | 29565.2 | 1 | UniProt (Q9F663) Pfam (PF00144) Pfam (PF13354) | Klebsiella pneumoniae | Carbapenem-hydrolyzing beta-lactamase KPC-1 |
| 2 | B (A) | {(3R,7S)-2-hydroxy-3-[2-(thiophen-2-yl)acetamido]-2,3,4,7-tetrahydro-1,2-oxaborepin-7-yl}acetic acid | non-polymer | 309.1 | 1 | Chemie (ZXQ) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A: 1 - 269 (UniProt: Q9F663)
| PDB | External Database | Details |
|---|---|---|
| Cys 270 | - | expression tag |
| Glu 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
| His 277 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29565.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 433.3 | |
| All* | Total formula weight | 29998.5 |
