7TI2

Structure of KPC-2 bound to RPX-7063 at 1.75A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Carbapenem-hydrolyzing beta-lactamase KPC	polymer	277	29565.2	1	UniProt (Q9F663) Pfam (PF00144) Pfam (PF13354) In PDB	Klebsiella pneumoniae	Carbapenem-hydrolyzing beta-lactamase KPC-1
2	A	{(3R,7S)-2-hydroxy-3-[2-(thiophen-2-yl)acetamido]-2,3,4,7-tetrahydro-1,2-oxaborepin-7-yl}acetic acid	non-polymer		309.1	1	Chemie (ZXQ)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4		water	water		18.0	311	Chemie (HOH)

Sequence modifications

A: 1 - 269 (UniProt: Q9F663)

PDB	External Database	Details
Cys 270	-	expression tag
Glu 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag
His 276	-	expression tag
His 277	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29565.2
Non-Polymers*	Number of molecules	3
	Total formula weight	433.3
All*	Total formula weight	29998.5

*Water molecules are not included.