7THT
CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (S, V, C) | Spike glycoprotein | polymer | 1121 | 124125.5 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | D, F, H (H, a, d) | DH1042 heavy chain | polymer | 122 | 13476.2 | 3 | Homo sapiens (human) | ||
| 3 | E, G, I (L, c, b) | DH1042 light chain | polymer | 106 | 11431.6 | 3 | Homo sapiens (human) | ||
| 4 | J (A) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | K, L, M, N, O... (B, D, E, F, G...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 6 | AA, AB, BA, BB, CA... (S, C, V) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 33 | Chemie (NAG) |
Sequence modifications
S, V, C: 27 - 1147 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Glu 607 | Gln 607 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 447099.8 | |
| Branched | Number of molecules | 13 |
| Total formula weight | 5679.4 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 7299.9 | |
| All* | Total formula weight | 460079.0 |
