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7THA

Crystal structure of human transthyretin variant C10A/M13V

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transthyretinpolymer12713713.22UniProt (P02766)
Pfam (PF00576)
Homo sapiens (human)ATTR,Prealbumin,TBPA
2C, D, E
(A, B)
CALCIUM IONnon-polymer40.13Chemie (CA)
3F, G
(A, B)
waterwater18.0154Chemie (HOH)
Sequence modifications
A, B: 1 - 127 (UniProt: P02766)
PDBExternal DatabaseDetails
Ala 10Cys 30engineered mutation
Val 13Met 33engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27426.5
Non-Polymers*Number of molecules3
Total formula weight120.2
All*Total formula weight27546.7
*Water molecules are not included.

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PDB entries from 2025-07-09

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