7TFP
Human Ornithine Aminotransferase cocrystallized with its inhibitor, (1S,3S)-3-amino-4-(difluoromethylene)cyclopentane-1-carboxylic acid.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Ornithine aminotransferase, mitochondrial | polymer | 404 | 44860.3 | 3 | UniProt (P04181) Pfam (PF00202) | Homo sapiens (human) | Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase |
| 2 | D, E, F (A, B, C) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 3 | Chemie (PLP) | |||
| 3 | G (C) | (1S,3S,4S)-3-amino-4-(fluoromethyl)cyclopentane-1-carboxylic acid | non-polymer | 161.2 | 1 | Chemie (I2V) | |||
| 4 | H, I, J (A, B, C) | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 134581.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 902.6 | |
| All* | Total formula weight | 135483.6 |
