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7TFP

Human Ornithine Aminotransferase cocrystallized with its inhibitor, (1S,3S)-3-amino-4-(difluoromethylene)cyclopentane-1-carboxylic acid.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, COrnithine aminotransferase, mitochondrialpolymer40444860.33UniProt (P04181)
Pfam (PF00202)
In PDB
Homo sapiens (human)Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase
2A, B, CPYRIDOXAL-5'-PHOSPHATEnon-polymer247.13Chemie (PLP)
3C(1S,3S,4S)-3-amino-4-(fluoromethyl)cyclopentane-1-carboxylic acidnon-polymer161.21Chemie (I2V)
4waterwater18.0252Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight134581.0
Non-Polymers*Number of molecules4
Total formula weight902.6
All*Total formula weight135483.6
*Water molecules are not included.

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