7TDH

Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in open conformation

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Ryanodine receptor 1,Ryanodine receptor 1,RyR1	polymer	5037	533663.3	4	UniProt (P11716) Pfam (PF08709) Pfam (PF01365) Pfam (PF02026) Pfam (PF08454) Pfam (PF06459) Pfam (PF00520) Pfam (PF02815) Pfam (PF00622) Pfam (PF21119) In PDB	Oryctolagus cuniculus (rabbit)	RYR-1,RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor
2	A, B, C, D	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	A, B, C, D	CALCIUM ION	non-polymer		40.1	8	Chemie (CA)
4	A, B, C, D	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	4	Chemie (ACP)

Sequence modifications

A, B, C, D: 1 - 1275 (UniProt: P11716)
A, B, C, D: 1276 - 1564 (PDB: 7TDH)
A, B, C, D: 1565 - 2486 (UniProt: P11716)
A, B, C, D: 2487 - 2703 (PDB: 7TDH)
A, B, C, D: 2704 - 2941 (UniProt: P11716)
A, B, C, D: 2942 - 3613 (PDB: 7TDH)
A, B, C, D: 3614 - 5037 (UniProt: P11716)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	2134653.0
Non-Polymers*	Number of molecules	16
	Total formula weight	2603.1
All*	Total formula weight	2137256.1

*Water molecules are not included.