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7TA3

Trimer-to-Monomer Disruption of Tumor Necrosis Factor-alpha (TNF-alpha) by alpha-peptide-3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Alpha-peptide-3polymer323604.02Synthetic construct
2B, D
(B, D)
Tumor necrosis factorpolymer15817457.72UniProt (P01375)
Pfam (PF00229)
Homo sapiens (human)Cachectin,TNF-alpha,Tumor necrosis factor ligand superfamily member 2,TNF-a
3E, F, G
(A, B, D)
waterwater18.013Chemie (HOH)
Sequence modifications
B, D: 1 - 157 (UniProt: P01375)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight42123.5
All*Total formula weight42123.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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