7TA3
Trimer-to-Monomer Disruption of Tumor Necrosis Factor-alpha (TNF-alpha) by alpha-peptide-3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Alpha-peptide-3 | polymer | 32 | 3604.0 | 2 | Synthetic construct | ||
| 2 | B, D (B, D) | Tumor necrosis factor | polymer | 158 | 17457.7 | 2 | UniProt (P01375) Pfam (PF00229) | Homo sapiens (human) | Cachectin,TNF-alpha,Tumor necrosis factor ligand superfamily member 2,TNF-a |
| 3 | E, F, G (A, B, D) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 157 (UniProt: P01375)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42123.5 | |
| All* | Total formula weight | 42123.5 |






