7T5Y
E. coli dihydroorotate dehydrogenase bound to the inhibitor HMNQ
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Dihydroorotate dehydrogenase (quinone) | polymer | 368 | 40285.3 | 2 | UniProt (P0A7E1) Pfam (PF01180) In PDB | Escherichia coli K-12 | DHOdehase,DHOD,DHODase,Dihydroorotate oxidase |
2 | A, B | 3-methyl-2-[(2E)-non-2-en-1-yl]quinolin-4(1H)-one | non-polymer | 283.4 | 2 | Chemie (F2D) | |||
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | A, B | OROTIC ACID | non-polymer | 156.1 | 2 | Chemie (ORO) | |||
5 | A, B | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) | |||
6 | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 336 (UniProt: P0A7E1)
PDB | External Database | Details |
---|---|---|
His -31 | - | expression tag |
His -30 | - | expression tag |
His -29 | - | expression tag |
His -28 | - | expression tag |
His -27 | - | expression tag |
His -26 | - | expression tag |
Ser -25 | - | expression tag |
Ser -24 | - | expression tag |
Gly -23 | - | expression tag |
Leu -22 | - | expression tag |
Val -21 | - | expression tag |
Pro -20 | - | expression tag |
Arg -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
Met -15 | - | expression tag |
Ala -14 | - | expression tag |
Ser -13 | - | expression tag |
Met -12 | - | expression tag |
Thr -11 | - | expression tag |
Gly -10 | - | expression tag |
Gly -9 | - | expression tag |
Gln -8 | - | expression tag |
Gln -7 | - | expression tag |
Met -6 | - | expression tag |
Gly -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 80570.5 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1886.7 | |
All* | Total formula weight | 82457.2 |