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7T4W

Crystal Structure of cGMP-dependent Protein Kinase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BcGMP-dependent protein kinase 1polymer46953177.12UniProt (Q13976)
Pfam (PF00027)
Pfam (PF00069)
In PDB
Homo sapiens (human)cGK 1,cGK1,cGMP-dependent protein kinase I,cGKI
2A, B(2R)-2-({(2S,3S)-1-[(1H-benzimidazol-2-yl)methyl]-2-phenylpiperidin-3-yl}oxy)-2-(3,5-dichlorophenyl)ethan-1-olnon-polymer496.42Chemie (EZJ)
3A, BCHLORIDE IONnon-polymer35.52Chemie (CL)
4waterwater18.0141Chemie (HOH)
Sequence modifications
A, B: 219 - 686 (UniProt: Q13976)
PDBExternal DatabaseDetails
Ser 218-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight106354.2
Non-Polymers*Number of molecules4
Total formula weight1063.8
All*Total formula weight107418.0
*Water molecules are not included.

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PDB entries from 2024-08-07

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