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7T4V

Crystal Structure of cGMP-dependent Protein Kinase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
cGMP-dependent protein kinase 1polymer46953177.12UniProt (Q13976)
Pfam (PF00027)
Pfam (PF00069)
Homo sapiens (human)cGK 1,cGK1,cGMP-dependent protein kinase I,cGKI
2C, E
(A, B)
4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)-3-methylbenzoic acidnon-polymer514.42Chemie (EXZ)
3D, F
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4G, H
(A, B)
waterwater18.0107Chemie (HOH)
Sequence modifications
A, B: 219 - 686 (UniProt: Q13976)
PDBExternal DatabaseDetails
Ser 218-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight106354.2
Non-Polymers*Number of molecules4
Total formula weight1099.8
All*Total formula weight107454.0
*Water molecules are not included.

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PDB entries from 2026-02-11

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