7T3F
Development of BRD4 inhibitors as arsenicals antidotes
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain-containing protein 4 | polymer | 127 | 15078.4 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
2 | A | 4-fluoro-3-methyl-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzene-1-sulfonamide | non-polymer | 349.4 | 1 | Chemie (EM0) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A: 44 - 167 (UniProt: O60885)
PDB | External Database | Details |
---|---|---|
Gly 41 | - | expression tag |
His 42 | - | expression tag |
Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15078.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 625.7 | |
All* | Total formula weight | 15704.0 |