7T3D
CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E, F | Hemagglutinin HA1 chain | polymer | 331 | 36729.4 | 3 | UniProt (C3W5S1) Pfam (PF00509) In PDB | Influenza A virus (A/California/04/2009(H1N1)) | |
2 | B, G, I | Hemagglutinin HA2 chain | polymer | 174 | 19977.1 | 3 | UniProt (C3W5S1) Pfam (PF00509) In PDB | Influenza A virus (A/California/04/2009(H1N1)) | |
3 | D, M, N | 2B05 mAb light chain | polymer | 107 | 11769.1 | 3 | Homo sapiens | ||
4 | C, J, K | 2B05 mAb heavy chain | polymer | 120 | 12805.2 | 3 | Homo sapiens | ||
5 | H, O, P | 222-1C06 mAb heavy chain | polymer | 122 | 13528.0 | 3 | Homo sapiens | ||
6 | L, Q, R | 222-1C06 mAb light chain | polymer | 108 | 11657.0 | 3 | Homo sapiens | ||
7 | S, T, U | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
8 | E, G, F, I, A... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) |
Sequence modifications
A, E, F: 11 - 329 (UniProt: C3W5S1)
B, G, I: 1 - 174 (UniProt: C3W5S1)
PDB | External Database | Details |
---|---|---|
Ala 7 | - | expression tag |
Asp 8 | - | expression tag |
Pro 9 | - | expression tag |
Gly 10 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Lys 47 | Glu 391 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 18 |
Total formula weight | 319397.7 | |
Branched | Number of molecules | 3 |
Total formula weight | 1273.2 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 3318.1 | |
All* | Total formula weight | 323989.0 |