7T39
Co-crystal structure of human PRMT9 in complex with MT221 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein arginine N-methyltransferase 9 | polymer | 720 | 80486.3 | 1 | UniProt (Q6P2P2) Pfam (PF06325) Pfam (PF22528) | Homo sapiens (human) | Protein arginine N-methyltransferase 10 |
| 2 | B (A) | 7-[5-S-(4-{[(2-ethylpyridin-3-yl)methyl]amino}butyl)-5-thio-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 472.6 | 1 | Chemie (EJB) | |||
| 3 | C (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 127 - 845 (UniProt: Q6P2P2)
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 80486.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 472.6 | |
| All* | Total formula weight | 80958.9 |
