7T2L
Crystal Structure of TEAD2 in a covalent complex with TED-662
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Transcriptional enhancer factor TEF-4 | polymer | 234 | 26627.2 | 2 | UniProt (Q15562) Pfam (PF17725) In PDB | Homo sapiens (human) | TEA domain family member 2,TEAD-2 |
| 2 | A | (3aR,4R,7aS)-4-[3-(trifluoromethyl)anilino]octahydro-2H-isoindole-2-carbonitrile | non-polymer | 309.3 | 1 | Chemie (EFI) | |||
| 3 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
B, A: 217 - 447 (UniProt: Q15562)
| PDB | External Database | Details |
|---|---|---|
| Gly 214 | - | expression tag |
| His 215 | - | expression tag |
| Met 216 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53254.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 309.3 | |
| All* | Total formula weight | 53563.7 |
