7T1F
Crystal structure of GDP-bound T50I mutant of human KRAS4B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Isoform 2B of GTPase KRas | polymer | 170 | 19340.9 | 3 | UniProt (P01116-2) Pfam (PF00071) UniProt (by SIFTS) (P01116) | Homo sapiens (human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | D, F, H (A, B, C) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 3 | E, G, I, J (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | K, L, M (A, B, C) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 169 (UniProt: P01116-2)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ile 50 | Thr 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58022.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1426.8 | |
| All* | Total formula weight | 59449.4 |
