7T1D
Human SIRT2 in complex with small molecule 359
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NAD-dependent protein deacetylase sirtuin-2 | polymer | 301 | 34090.3 | 2 | UniProt (Q8IXJ6) Pfam (PF02146) | Homo sapiens (human) | |
| 2 | C, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, K, L (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | F, G, M, N, O... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 5 | H, R (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 6 | I, S (A, B) | 7-(2,4-dimethyl-1H-imidazol-1-yl)-2-(5-{[4-(1H-pyrazol-1-yl)phenyl]methyl}-1,3-thiazol-2-yl)-1,2,3,4-tetrahydroisoquinoline | non-polymer | 466.6 | 2 | Chemie (E7K) | |||
| 7 | T, U (A, B) | water | water | 18.0 | 681 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68180.7 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2039.0 | |
| All* | Total formula weight | 70219.7 |
