7T0Y

The Ribosomal RNA Processing 1B Protein Phosphatase-1 Holoenzyme

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	polymer	299	34191.2	2	UniProt (P62136) Pfam (PF16891) Pfam (PF00149)	Homo sapiens (human)	PP-1A
2	B, D (B, D)	Ribosomal RNA processing protein 1 homolog B	polymer	47	5179.0	2	UniProt (Q14684)	Homo sapiens (human)	RRP1-like protein B
3	E, F, G, H, I... (A, C)	1,2-ETHANEDIOL	non-polymer		62.1	11	Chemie (EDO)
4	J, K, U, V (A, C)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
5	L (A)	FLUORIDE ION	non-polymer		19.0	1	Chemie (F)
6	M, N, W (A, C)	BROMIDE ION	non-polymer		79.9	3	Chemie (BR)
7	AA, X, Y, Z (D, A, B, C)	water	water		18.0	483	Chemie (HOH)

Sequence modifications

A, C: 7 - 300 (UniProt: P62136)

PDB	External Database	Details
Gly 2	-	expression tag
His 3	-	expression tag
Met 4	-	expression tag
Gly 5	-	expression tag
Ser 6	-	expression tag
Arg 20	Gln 20	engineered mutation

B, D: 682 - 727 (UniProt: Q14684)

PDB	External Database	Details
Gly 681	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	78740.5
Non-Polymers*	Number of molecules	19
	Total formula weight	1161.2
All*	Total formula weight	79901.7

*Water molecules are not included.