7SZR
NIK bound to inhibitor G02792917
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase kinase kinase 14 | polymer | 352 | 38801.7 | 2 | UniProt (Q9WUL6) Pfam (PF00069) | Mus musculus (house mouse) | NF-kappa-beta-inducing kinase,Serine/threonine-protein kinase NIK |
| 2 | C, D, E, F, H... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | G, J (A, B) | 1-(3-{[(1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2-azabicyclo[3.1.0]hexan-4-yl]ethynyl}phenyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide | non-polymer | 387.4 | 2 | Chemie (DYQ) |
Sequence modifications
A, B: 329 - 675 (UniProt: Q9WUL6)
| PDB | External Database | Details |
|---|---|---|
| Gly 327 | - | expression tag |
| Ser 328 | - | expression tag |
| Gly 676 | - | expression tag |
| Asn 677 | - | expression tag |
| Ser 678 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77603.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1351.2 | |
| All* | Total formula weight | 78954.5 |
