7SZQ
Human P300 complexed with an azaindazole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone acetyltransferase p300 | polymer | 389 | 45009.2 | 1 | UniProt (Q09472) Pfam (PF08214) | Homo sapiens (human) | p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein lactyltransferas p300,Protein propionyltransferase p300 |
| 2 | B (A) | 1-[1-(4-chlorophenyl)cyclopentane-1-carbonyl]-N-1H-pyrazolo[4,3-b]pyridin-5-yl-D-prolinamide | non-polymer | 437.9 | 1 | Chemie (ETL) | |||
| 3 | C (A) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 1279 - 1666 (UniProt: Q09472)
| PDB | External Database | Details |
|---|---|---|
| Gly 1278 | - | expression tag |
| Phe 1467 | Tyr 1467 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45009.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 437.9 | |
| All* | Total formula weight | 45447.1 |
