7SZB
Crystal Structure Analysis of human PRPK complex with a compound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | EKC/KEOPS complex subunit TP53RK | polymer | 255 | 28358.6 | 2 | UniProt (Q96S44) Pfam (PF06293) In PDB | Homo sapiens (Human) | Atypical serine/threonine protein kinase TP53RK,Nori-2,TP53-regulating kinase,p53-related protein kinase |
2 | B, D | EKC/KEOPS complex subunit TPRKB | polymer | 178 | 19976.2 | 2 | UniProt (Q9Y3C4) Pfam (PF08617) In PDB | Homo sapiens (Human) | PRPK-binding protein,TP53RK-binding protein |
3 | A, C | 5-amino-2-[(3R)-2,6-dioxopiperidin-3-yl]-1H-isoindole-1,3(2H)-dione | non-polymer | 273.2 | 2 | Chemie (DQ4) | |||
4 | A, C | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
5 | water | water | 18.0 | 493 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 253 (UniProt: Q96S44)
B, D: 1 - 175 (UniProt: Q9Y3C4)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Pro 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 96669.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 924.7 | |
All* | Total formula weight | 97594.4 |