7SYF

Reconstruction of full-length Prex-1 (PtdIns(3,4,5)P3-dependent Rac Exchanger 1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Endolysin chimera	polymer	1690	191463.0	1	UniProt (Q8TCU6) UniProt (D9IEF7) Pfam (PF00621) Pfam (PF22697) Pfam (PF00959) Pfam (PF00610) In PDB	Homo sapiens (human)	P-Rex1,PtdIns(3,4,5)-dependent Rac exchanger 1,Lysis protein,Lysozyme,Muramidase

Sequence modifications

A: 41 - 304 (UniProt: Q8TCU6)

PDB	External Database	Details
Met 20	-	expression tag
Gly 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
His 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
Ser 30	-	expression tag
Ser 31	-	expression tag
Gly 32	-	expression tag
Ser 33	-	expression tag
Glu 34	-	expression tag
Asn 35	-	expression tag
Leu 36	-	expression tag
Tyr 37	-	expression tag
Phe 38	-	expression tag
Gln 39	-	expression tag
Gly 40	-	expression tag

A: 304 - 310 (UniProt: D9IEF7)

PDB	External Database	Details
Thr 306	Cys 54	conflict
Ala 307	Cys 97	conflict

A: 310 - 1210 (UniProt: Q8TCU6)
A: 1212 - 1659 (UniProt: Q8TCU6)

PDB	External Database	Details
Thr 1211	-	linker
Glu 1340	Lys 1340	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	191463.0
All*	Total formula weight	191463.0

*Water molecules are not included.