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7SXH

BIO-8546 bound GSK3beta-axin complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glycogen synthase kinase-3 betapolymer34739553.41UniProt (P49841)
Pfam (PF00069)
Homo sapiens (Human)GSK-3 beta,Serine/threonine-protein kinase GSK3B
2B
(B)
axin peptidepolymer161911.21UniProt (by SIFTS) (O15169)Homo sapiens
3C
(A)
(4S,5R,8R)-4-ethyl-8-fluoro-4-[3-(3-fluoro-5-methoxypyridin-4-yl)phenyl]-7,7-dimethyl-4,5,6,7,8,9-hexahydro-2H-pyrazolo[3,4-b]quinolin-5-olnon-polymer466.51Chemie (D1E)
4D
(A)
waterwater18.0124Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight41464.5
Non-Polymers*Number of molecules1
Total formula weight466.5
All*Total formula weight41931.1
*Water molecules are not included.

248636

PDB entries from 2026-02-04

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