7SXF
BIO-2895 (BRD0705) bound GSK3alpha-axin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycogen synthase kinase-3 alpha | polymer | 345 | 39292.2 | 1 | UniProt (P49840) Pfam (PF00069) | Homo sapiens (Human) | GSK-3 alpha,Serine/threonine-protein kinase GSK3A |
| 2 | B (B) | Axin peptide | polymer | 17 | 2009.4 | 1 | UniProt (by SIFTS) (O15169) | Homo sapiens | |
| 3 | C (A) | (4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one | non-polymer | 321.4 | 1 | Chemie (6VL) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A: 101 - 444 (UniProt: P49840)
| PDB | External Database | Details |
|---|---|---|
| Arg 445 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41301.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 361.5 | |
| All* | Total formula weight | 41663.1 |
