7SX4
Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 2/2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium leak channel non-selective protein,Enhanced green fluorescent protein | polymer | 2042 | 234128.8 | 1 | UniProt (Q8IZF0) UniProt (A0A7G8ZY66) Pfam (PF00520) | Homo sapiens (human) | CanIon,Voltage gated channel-like protein 1 |
| 2 | B (B) | Transmembrane protein FAM155A | polymer | 483 | 54205.0 | 1 | UniProt (B1AL88) | Homo sapiens (human) | |
| 3 | C (C) | Calmodulin-1 | polymer | 149 | 16852.5 | 1 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 4 | D (D) | UNC79,Protein unc-79 homolog | polymer | 2561 | 285174.9 | 1 | UniProt (Q9P2D8) Pfam (PF14776) | Homo sapiens | |
| 5 | E (E) | Protein unc-80 homolog | polymer | 3283 | 366510.6 | 1 | UniProt (Q8N2C7) Pfam (PF19424) Pfam (PF20262) Pfam (PF15778) | Homo sapiens (human) | |
| 6 | F, G (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | H (A) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 720.0 | 1 | Chemie (PEV) PubChem (5326793) PubChem (9546967) PubChem (16040250) | |||
| 8 | I (A) | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE | non-polymer | 749.0 | 1 | Chemie (PGV) PubChem (5289145) PubChem (21158857) PubChem (73746220) PubChem (162368821) PubChem (163029036) | |||
| 9 | J, K, L (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 3 | Chemie (Y01) PubChem (65082) PubChem (363416) PubChem (500055) PubChem (13301926) PubChem (13301927) PubChem (16219150) PubChem (22210610) PubChem (45489984) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A: 1 - 1738 (UniProt: Q8IZF0)
A: 1760 - 2000 (UniProt: A0A7G8ZY66)
B: 1 - 458 (UniProt: B1AL88)
D: 38 - 165 (PDB: 7SX4)
D: 174 - 2635 (UniProt: Q9P2D8)
E: 1 - 3258 (UniProt: Q8N2C7)
| PDB | External Database | Details |
|---|---|---|
| Gly 1739 | - | linker |
| Gly 1740 | - | linker |
| Ser 1741 | - | linker |
| Leu 1742 | - | linker |
| Val 1743 | - | linker |
| Pro 1744 | - | linker |
| Arg 1745 | - | linker |
| Gly 1746 | - | linker |
| Ser 1747 | - | linker |
| Ser 1748 | - | linker |
| Gly 1749 | - | linker |
| Glu 1750 | - | linker |
| Asn 1751 | - | linker |
| Leu 1752 | - | linker |
| Tyr 1753 | - | linker |
| Phe 1754 | - | linker |
| Gln 1755 | - | linker |
| Gly 1756 | - | linker |
| Ser 1757 | - | linker |
| Ser 1758 | - | linker |
| Gly 1759 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Lys 1966 | Ala 207 | conflict |
| Gly 2001 | - | expression tag |
| Asp 2002 | - | expression tag |
| Tyr 2003 | - | expression tag |
| Lys 2004 | - | expression tag |
| Asp 2005 | - | expression tag |
| Asp 2006 | - | expression tag |
| Asp 2007 | - | expression tag |
| Asp 2008 | - | expression tag |
| Lys 2009 | - | expression tag |
| Gly 2010 | - | expression tag |
| Ser 2011 | - | expression tag |
| Gly 2012 | - | expression tag |
| Ser 2013 | - | expression tag |
| Ala 2014 | - | expression tag |
| Trp 2015 | - | expression tag |
| Ser 2016 | - | expression tag |
| His 2017 | - | expression tag |
| Pro 2018 | - | expression tag |
| Gln 2019 | - | expression tag |
| Phe 2020 | - | expression tag |
| Glu 2021 | - | expression tag |
| Lys 2022 | - | expression tag |
| Gly 2023 | - | expression tag |
| Gly 2024 | - | expression tag |
| Gly 2025 | - | expression tag |
| Ser 2026 | - | expression tag |
| Gly 2027 | - | expression tag |
| Gly 2028 | - | expression tag |
| Gly 2029 | - | expression tag |
| Ser 2030 | - | expression tag |
| Gly 2031 | - | expression tag |
| Gly 2032 | - | expression tag |
| Ser 2033 | - | expression tag |
| Ala 2034 | - | expression tag |
| Trp 2035 | - | expression tag |
| Ser 2036 | - | expression tag |
| His 2037 | - | expression tag |
| Pro 2038 | - | expression tag |
| Gln 2039 | - | expression tag |
| Phe 2040 | - | expression tag |
| Glu 2041 | - | expression tag |
| Lys 2042 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 459 | - | expression tag |
| Gly 460 | - | expression tag |
| Ser 461 | - | expression tag |
| Gly 462 | - | expression tag |
| Gly 463 | - | expression tag |
| Ser 464 | - | expression tag |
| Asp 465 | - | expression tag |
| Tyr 466 | - | expression tag |
| Lys 467 | - | expression tag |
| Asp 468 | - | expression tag |
| Asp 469 | - | expression tag |
| Asp 470 | - | expression tag |
| Asp 471 | - | expression tag |
| Lys 472 | - | expression tag |
| Gly 473 | - | expression tag |
| Asn 474 | - | expression tag |
| Ser 475 | - | expression tag |
| Asp 476 | - | expression tag |
| Tyr 477 | - | expression tag |
| Lys 478 | - | expression tag |
| Asp 479 | - | expression tag |
| Asp 480 | - | expression tag |
| Asp 481 | - | expression tag |
| Asp 482 | - | expression tag |
| Lys 483 | - | expression tag |
D: 174 - 2635 (UniProt: Q9P2D8)
| PDB | External Database | Details |
|---|---|---|
| Gly 2636 | - | expression tag |
| Gly 2637 | - | expression tag |
| Ser 2638 | - | expression tag |
| Gly 2639 | - | expression tag |
| Gly 2640 | - | expression tag |
| Ser 2641 | - | expression tag |
| Asp 2642 | - | expression tag |
| Tyr 2643 | - | expression tag |
| Lys 2644 | - | expression tag |
| Asp 2645 | - | expression tag |
| Asp 2646 | - | expression tag |
| Asp 2647 | - | expression tag |
| Asp 2648 | - | expression tag |
| Lys 2649 | - | expression tag |
| Gly 2650 | - | expression tag |
| Asn 2651 | - | expression tag |
| Ser 2652 | - | expression tag |
| Asp 2653 | - | expression tag |
| Tyr 2654 | - | expression tag |
| Lys 2655 | - | expression tag |
| Asp 2656 | - | expression tag |
| Asp 2657 | - | expression tag |
| Asp 2658 | - | expression tag |
| Asp 2659 | - | expression tag |
| Lys 2660 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 3259 | - | expression tag |
| Gly 3260 | - | expression tag |
| Ser 3261 | - | expression tag |
| Gly 3262 | - | expression tag |
| Gly 3263 | - | expression tag |
| Ser 3264 | - | expression tag |
| Asp 3265 | - | expression tag |
| Tyr 3266 | - | expression tag |
| Lys 3267 | - | expression tag |
| Asp 3268 | - | expression tag |
| Asp 3269 | - | expression tag |
| Asp 3270 | - | expression tag |
| Asp 3271 | - | expression tag |
| Lys 3272 | - | expression tag |
| Gly 3273 | - | expression tag |
| Asn 3274 | - | expression tag |
| Ser 3275 | - | expression tag |
| Asp 3276 | - | expression tag |
| Tyr 3277 | - | expression tag |
| Lys 3278 | - | expression tag |
| Asp 3279 | - | expression tag |
| Asp 3280 | - | expression tag |
| Asp 3281 | - | expression tag |
| Asp 3282 | - | expression tag |
| Lys 3283 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 956871.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3371.6 | |
| All* | Total formula weight | 960243.5 |
