7SVR
The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cystic fibrosis transmembrane conductance regulator | polymer | 1480 | 168335.5 | 1 | UniProt (P13569) Pfam (PF00664) Pfam (PF00005) Pfam (PF14396) | Homo sapiens (human) | CFTR,ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel |
| 2 | B (B) | Cystic fibrosis transmembrane conductance regulator | polymer | 19 | 1635.0 | 1 | Homo sapiens (human) | ||
| 3 | C (A) | Lumacaftor | non-polymer | 452.4 | 1 | Chemie (VX8) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 169970.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 452.4 | |
| All* | Total formula weight | 170422.9 |
