7SVO
DPP8 IN COMPLEX WITH LIGAND ICeD-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Dipeptidyl peptidase 8 | polymer | 903 | 103886.8 | 3 | UniProt (Q6V1X1) Pfam (PF19520) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (human) | DP8,Dipeptidyl peptidase IV-related protein 1,DPRP-1,Dipeptidyl peptidase VIII,DPP VIII,Prolyl dipeptidase DPP8 |
| 2 | D, G, N (A, B, C) | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile | non-polymer | 253.3 | 3 | Chemie (CW8) | |||
| 3 | E, F, H, I, J... (A, B, C) | trimethylamine oxide | non-polymer | 75.1 | 11 | Chemie (TMO) | |||
| 4 | R, S, T (A, B, C) | water | water | 18.0 | 702 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 898 (UniProt: Q6V1X1)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 311660.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1586.2 | |
| All* | Total formula weight | 313246.6 |
