7SU6

DIHYDRONEOPTERIN ALDOLASE (DHNA) Lys98Ala FROM YERSINIA PESTIS CO-CRYSTALLIZED with 7,8-dihydroneopterin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	7,8-dihydroneopterin aldolase	polymer	143	16091.1	4	UniProt (Q8CZR7) Pfam (PF02152) UniProt (by SIFTS) (A0A5P8YJX5)	Yersinia pestis
2	E, G, I, J (A, B, C, D)	2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE	non-polymer		255.2	4	Chemie (NPR)
3	F, H (A, B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
4	K, L, M, N (A, B, C, D)	water	water		18.0	293	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 119 (UniProt: Q8CZR7)

PDB	External Database	Details
Met -23	-	initiating methionine
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag
Ala 98	Lys 99	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	64364.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1257.3
All*	Total formula weight	65621.5

*Water molecules are not included.