7SSM
Crystal structure of human STING R232 in complex with compound 11
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Stimulator of interferon genes protein | polymer | 210 | 24053.9 | 1 | UniProt (A0A2R3XZB7) Pfam (PF15009) UniProt (by SIFTS) (Q86WV6) In PDB | Homo sapiens (Human) | Transmembrane protein 173 |
2 | A | 2-({[(8R)-pyrazolo[1,5-a]pyrimidine-3-carbonyl]amino}methyl)-1-benzofuran-7-carboxylic acid | non-polymer | 336.3 | 1 | Chemie (B7L) | |||
3 | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A: 155 - 341 (UniProt: A0A2R3XZB7)
PDB | External Database | Details |
---|---|---|
Met 132 | - | expression tag |
Gly 133 | - | expression tag |
Ser 134 | - | expression tag |
Ser 135 | - | expression tag |
His 136 | - | expression tag |
His 137 | - | expression tag |
His 138 | - | expression tag |
His 139 | - | expression tag |
His 140 | - | expression tag |
His 141 | - | expression tag |
Ser 142 | - | expression tag |
Ser 143 | - | expression tag |
Gly 144 | - | expression tag |
Glu 145 | - | expression tag |
Thr 146 | - | expression tag |
Val 147 | - | expression tag |
Arg 148 | - | expression tag |
Phe 149 | - | expression tag |
Gln 150 | - | expression tag |
Gly 151 | - | expression tag |
His 152 | - | expression tag |
Met 153 | - | expression tag |
Ser 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 24053.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 336.3 | |
All* | Total formula weight | 24390.2 |