7SSH

Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, AA, C, CA, E... (A, C, E, G, I...)	Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera	polymer	429	48214.9	16	UniProt (P03129) UniProt (P16213) UniProt (A0A678ZGP6) Pfam (PF07654) Pfam (PF00129)	Human papillomavirus type 16
2	B, BA, D, DA, F... (B, D, F, H, J...)	VHH	polymer	116	12536.8	16		Lama glama
3	AB, BB, CB, DB, EB... (U, V, W, X, Y...)	water	water		18.0	282	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e: 1 - 10 (UniProt: P03129)

PDB	External Database	Details
Gly 10	-	linker
Gly 10	-	linker
Gly 10	-	linker
Gly 10	-	linker
Ser 10	-	linker
Gly 10	-	linker
Gly 10	-	linker
Gly 10	-	linker
Gly 10	-	linker
Ser 10	-	linker
Gly 10	-	linker
Gly 10	-	linker
Gly 10	-	linker
Gly 10	-	linker
Ser 10	-	linker

A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e: 25 - 123 (UniProt: P16213)

PDB	External Database	Details
Gly 124	-	linker
Gly 125	-	linker
Gly 126	-	linker
Gly 127	-	linker
Ser 128	-	linker
Gly 129	-	linker
Gly 130	-	linker
Gly 131	-	linker
Gly 132	-	linker
Ser 133	-	linker
Gly 134	-	linker
Gly 135	-	linker
Gly 136	-	linker
Gly 137	-	linker
Ser 138	-	linker
Gly 139	-	linker
Gly 140	-	linker
Gly 141	-	linker
Gly 142	-	linker
Ser 143	-	linker

A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e: 144 - 418 (UniProt: A0A678ZGP6)

PDB	External Database	Details
Ala 227	Tyr 108	engineered mutation
His 419	-	expression tag
His 420	-	expression tag
His 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag
His 424	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	32
	Total formula weight	972028.3
All*	Total formula weight	972028.3

*Water molecules are not included.