7SRQ
5-HT2B receptor bound to LSD obtained by cryo-electron microscopy (cryoEM)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | R | 5-hydroxytryptamine receptor 2B | polymer | 311 | 35052.6 | 1 | UniProt (P41595) Pfam (PF00001) In PDB | Homo sapiens (Human) | 5-HT-2B,5-HT2B,Serotonin receptor 2B |
| 2 | R | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | R | (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide | non-polymer | 323.4 | 1 | Chemie (7LD) |
Sequence modifications
R: 36 - 405 (UniProt: P41595)
| PDB | External Database | Details |
|---|---|---|
| Trp 144 | Met 144 | conflict |
| - | Lys 246 | deletion |
| - | Lys 247 | deletion |
| - | Ala 248 | deletion |
| - | Tyr 249 | deletion |
| - | Leu 250 | deletion |
| - | Val 251 | deletion |
| - | Lys 252 | deletion |
| - | Asn 253 | deletion |
| - | Lys 254 | deletion |
| - | Pro 255 | deletion |
| - | Pro 256 | deletion |
| - | Gln 257 | deletion |
| - | Arg 258 | deletion |
| - | Leu 259 | deletion |
| - | Thr 260 | deletion |
| - | Trp 261 | deletion |
| - | Leu 262 | deletion |
| - | Thr 263 | deletion |
| - | Val 264 | deletion |
| - | Ser 265 | deletion |
| - | Thr 266 | deletion |
| - | Val 267 | deletion |
| - | Phe 268 | deletion |
| - | Gln 269 | deletion |
| - | Arg 270 | deletion |
| - | Asp 271 | deletion |
| - | Glu 272 | deletion |
| - | Thr 273 | deletion |
| - | Pro 274 | deletion |
| - | Cys 275 | deletion |
| - | Ser 276 | deletion |
| - | Ser 277 | deletion |
| - | Pro 278 | deletion |
| - | Glu 279 | deletion |
| Arg 307 | Ala 282 | conflict |
| Leu 308 | Met 283 | conflict |
| Ser 310 | Asp 285 | conflict |
| - | Lys 289 | deletion |
| - | Asp 290 | deletion |
| - | Lys 291 | deletion |
| - | Ala 292 | deletion |
| - | Leu 293 | deletion |
| - | Pro 294 | deletion |
| - | Asn 295 | deletion |
| - | Ser 296 | deletion |
| - | Gly 297 | deletion |
| - | Asp 298 | deletion |
| - | Glu 299 | deletion |
| - | Thr 300 | deletion |
| - | Leu 301 | deletion |
| - | Met 302 | deletion |
| - | Arg 303 | deletion |
| - | Arg 304 | deletion |
| - | Thr 305 | deletion |
| - | Ser 306 | deletion |
| - | Thr 307 | deletion |
| - | Ile 308 | deletion |
| - | Gly 309 | deletion |
| - | Lys 310 | deletion |
| - | Lys 311 | deletion |
| - | Ser 312 | deletion |
| - | Val 313 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35052.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 544.6 | |
| All* | Total formula weight | 35597.3 |
