7SR5
Single chain trimer HLA-A*02:01 (Y108C, A163C) with Wilms tumor protein peptide RMFPNAPYL
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Wilms tumor protein peptide,Beta-2-microglobulin,MHC class I antigen chimera | polymer | 424 | 47683.5 | 2 | UniProt (P19544) UniProt (P16213) UniProt (A0A678ZGP6) Pfam (PF07654) Pfam (PF00129) UniProt (by SIFTS) (A0A6S7XV52) In PDB | Homo sapiens (Human) | WT33 |
2 | B, D | VHH | polymer | 116 | 12536.8 | 2 | Lama glama | ||
3 | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 9 (UniProt: P19544)
A, C: 25 - 123 (UniProt: P16213)
A, C: 144 - 418 (UniProt: A0A678ZGP6)
PDB | External Database | Details |
---|---|---|
Gly 10 | - | linker |
Gly 11 | - | linker |
Gly 12 | - | linker |
Gly 13 | - | linker |
Ser 14 | - | linker |
Gly 15 | - | linker |
Gly 16 | - | linker |
Gly 17 | - | linker |
Gly 18 | - | linker |
Ser 19 | - | linker |
Gly 20 | - | linker |
Gly 21 | - | linker |
Gly 22 | - | linker |
Gly 23 | - | linker |
Ser 24 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 124 | - | linker |
Gly 125 | - | linker |
Gly 126 | - | linker |
Gly 127 | - | linker |
Ser 128 | - | linker |
Gly 129 | - | linker |
Gly 130 | - | linker |
Gly 131 | - | linker |
Gly 132 | - | linker |
Ser 133 | - | linker |
Gly 134 | - | linker |
Gly 135 | - | linker |
Gly 136 | - | linker |
Gly 137 | - | linker |
Ser 138 | - | linker |
Gly 139 | - | linker |
Gly 140 | - | linker |
Gly 141 | - | linker |
Gly 142 | - | linker |
Ser 143 | - | linker |
PDB | External Database | Details |
---|---|---|
Cys 227 | Tyr 108 | engineered mutation |
Cys 282 | Ala 163 | engineered mutation |
His 419 | - | expression tag |
His 420 | - | expression tag |
His 421 | - | expression tag |
His 422 | - | expression tag |
His 423 | - | expression tag |
His 424 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 120440.6 | |
All* | Total formula weight | 120440.6 |