7SPT

Crystal structure of exofacial state human glucose transporter GLUT3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Solute carrier family 2, facilitated glucose transporter member 3	polymer	523	57080.1	1	UniProt (P11169) Pfam (PF00083)	Homo sapiens (Human)	Glucose transporter type 3,brain,GLUT-3
2	B, C, D (A)	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	non-polymer		356.5	3	Chemie (OLC)
3	E (A)	alpha-D-glucopyranose	non-polymer		180.2	1	Chemie (GLC)
4	F (A)	water	water		18.0	223	Chemie (HOH)

Sequence modifications

A: 1 - 496 (UniProt: P11169)

PDB	External Database	Details
Met -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Asp -13	-	expression tag
Glu -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Ala -9	-	expression tag
Gly -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Gln -5	-	expression tag
Val -4	-	expression tag
Asp -3	-	expression tag
Ala -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag
Thr 43	Asn 43	engineered mutation
Trp 64	Ser 64	engineered mutation
Trp 305	Ile 305	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	57080.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1249.8
All*	Total formula weight	58329.9

*Water molecules are not included.