7SPP

Crystal structure of the SARS-CoV-2 receptor binding domain in complex with VNAR 2C02

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Spike protein S1	polymer	225	25520.7	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2 COVID-19 virus)
2	B (C)	VNAR 2C02	polymer	117	13017.5	1		Squalus acanthias (llama)
3	C, E (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	D (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	F (C)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6	G, H (A, C)	water	water		18.0	128	Chemie (HOH)

Sequence modifications

A: 319 - 535 (UniProt: P0DTC2)

PDB	External Database	Details
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38538.2
Non-Polymers*	Number of molecules	4
	Total formula weight	380.8
All*	Total formula weight	38919.0

*Water molecules are not included.