7SOR

LaM domain of human LARP1 in complex with AAA RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Isoform 2 of La-related protein 1	polymer	99	11806.5	2	UniProt (Q6PKG0-3) Pfam (PF05383) UniProt (by SIFTS) (Q6PKG0)	Homo sapiens (Human)	La ribonucleoprotein domain family member 1
2	B, D (B, D)	RNA (5'-R(*AP*AP*A)-3')	polymer	3	942.7	2		synthetic construct
3	E, G (A, C)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	F (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	H, I, J, K (A, B, C, D)	water	water		18.0	157	Chemie (HOH)

Sequence modifications

A, C: 323 - 410 (UniProt: Q6PKG0-3)

PDB	External Database	Details
Met 312	-	initiating methionine
Gly 313	-	expression tag
Ser 314	-	expression tag
Ser 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
Ser 322	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	25498.3
Non-Polymers*	Number of molecules	3
	Total formula weight	159.6
All*	Total formula weight	25657.9

*Water molecules are not included.