7SLP
Cryo-EM structure of 7SK core RNP with linear RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 7SK snRNA methylphosphate capping enzyme | polymer | 309 | 35122.8 | 1 | UniProt (Q7L2J0) Pfam (PF06859) | Homo sapiens (human) | MePCE,Bicoid-interacting protein 3 homolog,Bin3 homolog |
| 2 | B (B) | La-related protein 7 | polymer | 480 | 55109.1 | 1 | UniProt (Q4G0J3) Pfam (PF05383) Pfam (PF00076) Pfam (PF08777) | Homo sapiens (human) | La ribonucleoprotein domain family member 7,hLARP7,P-TEFb-interaction protein for 7SK stability,PIP7S |
| 3 | C (R) | Linear 7SK RNA | polymer | 81 | 26096.2 | 1 | Homo sapiens | ||
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (177678424) PubChem (52224398) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (6419189) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (164157219) PubChem (118374891) PubChem (118560068) PubChem (5284331) PubChem (126969526) PubChem (129105892) PubChem (71170554) PubChem (143518505) PubChem (154578335) PubChem (13231890) PubChem (163054214) PubChem (163335525) |
Sequence modifications
A: 400 - 689 (UniProt: Q7L2J0)
B: 1 - 369 (UniProt: Q4G0J3)
B: 370 - 582 (UniProt: Q4G0J3)
| PDB | External Database | Details |
|---|---|---|
| Met 381 | - | expression tag |
| Gly 382 | - | expression tag |
| Ser 383 | - | expression tag |
| Ser 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
| His 389 | - | expression tag |
| His 390 | - | expression tag |
| Ser 391 | - | expression tag |
| Ser 392 | - | expression tag |
| Gly 393 | - | expression tag |
| Leu 394 | - | expression tag |
| Val 395 | - | expression tag |
| Pro 396 | - | expression tag |
| Arg 397 | - | expression tag |
| Gly 398 | - | expression tag |
| Ser 399 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 116328.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 116712.6 |
