7SLP

Cryo-EM structure of 7SK core RNP with linear RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0005634	cellular_component	nucleus
B	0006396	biological_process	RNA processing
B	1990904	cellular_component	ribonucleoprotein complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30559425","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DCB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30559425","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2009","submissionDatabase":"PDB data bank","title":"Methyltransferase domain of human bicoid-interacting protein 3 homolog (drosophila).","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"5UNA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DCC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	113
Details	Domain: {"description":"xRRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU01288","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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