7SJ2
N-acetylglucosamine-1-phosphotransferase (GNPT) alpha and beta subunits (GNPTAB) catalytic domain, from zebrafish, in complex with uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) and magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | N-acetylglucosamine-1-phosphotransferase subunit alpha,N-acetylglucosamine-1-phosphotransferase (GNPT) alpha (GNPTAB) catalytic domain,N-acetylglucosamine-1-phosphotransferase subunit beta | polymer | 495 | 58363.0 | 2 | UniProt (Q5RGJ8) UniProt (Q54MP1) Pfam (PF17101) Pfam (PF11380) Pfam (PF17102) Pfam (PF17103) In PDB | Danio rerio (Zebrafish Brachydanio rerio) | |
| 2 | C | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 3 | D, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 4 | E | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 5 | F | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 7 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 9 | A, B | URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | non-polymer | 607.4 | 2 | Chemie (UD1) | |||
| 10 | water | water | 18.0 | 768 | Chemie (HOH) |
Sequence modifications
A, B: 44 - 91 (UniProt: Q5RGJ8)
A, B: 92 - 130 (UniProt: Q54MP1)
A, B: 131 - 248 (UniProt: Q5RGJ8)
A, B: 249 - 528 (UniProt: Q5RGJ8)
| PDB | External Database | Details |
|---|---|---|
| Asp 34 | - | expression tag |
| Arg 35 | - | expression tag |
| His 36 | - | expression tag |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
| His 39 | - | expression tag |
| His 40 | - | expression tag |
| His 41 | - | expression tag |
| Gly 42 | - | expression tag |
| Ser 43 | - | expression tag |
A, B: 131 - 248 (UniProt: Q5RGJ8)
A, B: 249 - 528 (UniProt: Q5RGJ8)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116726.0 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3005.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2276.9 | |
| All* | Total formula weight | 122008.7 |
